Mapk )/ Extracellular Signal Background InformationOn November 10 2015 FDA issued an Approval Letter allowing Genentech

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Assignment: Cobimetinib (Cotellic) is an inhibitor of the mitogen-activated protein kinase (MAPK)/extracellular signal regulated kinase 1 (MEK1) and MEK2. These proteins are upstream regulators of the extracellular signal-related kinase (ERK)