What is the most common cause of this patient’s condition, and what is the pathogenesis of this disorder?

What is the most common cause of this patient’s condition, and what is the pathogenesis of this disorder?

A 25-year-old woman presents with a complaint of rapid weight loss despite a voracious
appetite. Physical examination reveals tachycardia (pulse rate 110 bpm at rest), fine moist skin, a
symmetrically enlarged thyroid, mild bilateral quadriceps muscle weakness, and fine tremor.
These findings strongly suggest hyperthyroidism.
A. What other features of the history should be elicited?
B. What other physical findings should be sought?
C. Serum TSH and free thyroxine level are ordered. What results should be anticipated?
D. What are the possible causes of this patient’s condition?
E. What is the most common cause of this patient’s condition, and what is the pathogenesis of
this disorder?
F. What is the pathogenesis of this patient’s tachycardia, weight loss, skin changes, goiter, and
muscle weakness?

Answer preview What is the most common cause of this patient’s condition, and what is the pathogenesis of this disorder?

What is the most common cause of this patient’s condition and what is the pathogenesis of this disorder?

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