Protein aggregation and deposition is responsible for dozens of human diseases.

Protein aggregation and deposition is responsible for dozens of human diseases.

Protein aggregation and deposition is responsible for dozens of human diseases. A research career on a major human disease is attractive both in academic and industry. To learn some basics, please review Type II diabetes and explain the role of protein aggregation in the early process of the disease.

Provide the following information in three pages long:

1) The protein or its fragment involved. Provide the protein or peptide’s isoelectric point, and molecular weight.

2) Is the structure of the aggregate amorphous or amyloid fiber?

3) Are oligomers formed during aggregation and the size of the oligomer if known?

4) What are the tissues the aggregates deposit?

5) What is the disease symptom, age of onset, life expectancy after diagnosis, cost to the society, methods of diagnosis, current treatment?

6) Are there any known risk factors for the disease?

7) List the companies that are researching on the disease.

Provide references supporting your statement.